HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E1611 Atuzabrutinib Jul 25 2024
E1791 Zongertinib Jul 25 2024
E1931 AD-5584 Jul 25 2024
E1533 Lipofermata Jul 25 2024
E1877 BLU 451(LNG-451) Jul 24 2024
E4827 Diphenhydramine Jul 23 2024
E1889 PCO371 Jul 23 2024
E1985 YD23 Jul 23 2024
E4835 Sumatriptan Jul 23 2024
E4836 Bupivacaine Jul 23 2024
E1961 NVL-655 Jul 23 2024
E1015 Angiotensin II human Jul 23 2024
E4837 Trimethoprim (lactate) Jul 23 2024
E4647 Aticaprant Jul 23 2024
E1957 NX-1607 Jul 23 2024
E4826 L-Ornithine L-aspartate L-ornithine-L-aspartate (LOLA) is a stable salt composed of two natural nonessential L-amino acids: ornithine and aspartic acid. It effectively lowers blood ammonia concentration by enhancing ammonia detoxification in the muscles, and alleviating hepatic encephalopathy symptoms in liver cirrhosis. Jul 19 2024
E4822 Tacrine Tacrine is a potent acetylcholinesterase (AChE) inhibitor. It inhibits acetylcholinesterase(AChE) and butyrylcholinesterase(BChE) with an IC50 of 77 nM and 69 nM, respectively. It is used in the treatment of Alzheimer's disease (AD), also poisoning topoisomerases and inhibiting in vivo (mitochondrial)mtDNA synthesis. Jul 19 2024
E4832 DL-Alanine DL-alanine (DL-2-Aminopropionic acid) is a racemic mixture of L- and D-alanine that forms complexes with transition metals like Cu(II), Zn(II), and Cd(II). It also plays a key role in the glucose-alanine cycle between tissues and the liver. Jul 19 2024
E4831 L-Arginine (L-glutamate) L-Arginine (L-glutamate) (Arginine glutamate) is a mixture of amino acids that induces apoptosis via hypertonic stress. It also promotes gastric relaxation by providing L-arginine for nitric oxide production, thereby benefiting gastrointestinal motility and conditions associated with vagus nerve dysfunction. Jul 19 2024
E4830 Guanidine thiocyanate Guanidine thiocyanate is a potent inhibitor of nucleases and a powerful denaturant of proteins. It is used for RNA isolation due to its strong chaotropic properties, which effectively denature RNase enzymes in samples, ensuring RNA stability and purity during extraction processes. Nucleic acid extraction buffers containing guanidine thiocyanate effectively deactivate high-titer polioviruses found in potentially infectious materials. Jul 19 2024
E4825 Naphazoline (nitrate) Naphazoline (nitrate) is a agonist of peripheral α2-adrenergic receptor and used as a topical decongestant. It also acts as a vasoconstrictor that effectively reduces intraoperative bleeding and enhances postoperative analgesia. When used in conjunction with intranasal lidocaine, it significantly reduces both intra- and postoperative pain, thereby decreasing the need for rescue analgesics in the postoperative period following septorhinoplasty. Jul 19 2024
E4828 Cloperastine fendizoate Cloperastine fendizoate (Hustazol) is a sedative used to relieve cough and also has a peripheral action that desensitizes the afferent nerves in the tracheobronchial region. It inhibits the hERG K+ currents in a concentration-dependent manner, with an IC50 value of 0.027 μM. Jul 19 2024
E4824 Hydroxychloroquine Hydroxychloroquine (HCQ) is an antimalarial drug that inhibits autophagy and is used to treat systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). It exhibits immunomodulatory, antithrombotic, and antiplatelet properties. It inhibits the release endothelin-1, a potent vasoconstrictor, and restores impaired angiogenesis in TNF-α-treated endothelial cells in vitro. It also reduces the production of inflammatory cytokines such as TNF-α, IFN-γ, and IL-6 from peripheral blood mononuclear cells, upregulates IL-10 and decreases platelet aggregation. Jul 19 2024
E4806 Quinine dihydrochloride Quinine dihydrochloride is an antiparasitic used to treat malaria and is particularly important for managing malaria during the first trimester of pregnancy. It inhibits Slo3 (KCa 5.1) channel, which are a significant part of the mammalian KSper (sperm potassium conductance), by binding to hydrophobic side chains located at the intracellular region of the channel pore. Jul 19 2024
E1885 LY3522348 LY3522348 is a highly selective oral dual inhibitor of the human ketohexokinase isoforms C and A, with IC50 values of 20nM for hKHK-C and 24nM for hKHK-A. It shows a significant pharmacodynamic effect in a mouse model of fructose metabolism. Jul 19 2024
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