Home Biosimilar Antibodies Protein Tyrosine Kinase VEGFR antibody Ranibizumab (Anti-VEGFA) For research use only.
Not for use in humans.

Ranibizumab (Anti-VEGFA)

Synonyms: Lucentis

Ranibizumab (Anti-VEGFA) is a recombinant humanized IgG1 monoclonal antibody fragment that inhibits (VEGF-A) and degrades angiogenesis throughout the body and in the eye also interrupts the interaction of VEGF with its receptors, and thus prevents the subsequent growth of new blood vessels.

Ranibizumab (Anti-VEGFA)

Purity & Quality Control

Batch: A230501 Purity: 99% Protein concentration: 3.61mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective VEGFR Inhibitors

Name Citation VEGFR1 VEGFR2 VEGFR3 Others
Foretinib 93 Met,Tie-2,RON
Cediranib (AZD2171) 67 c-Kit,PDGFRβ,FGFR1
PD173074 123 FGFR1
Dovitinib (TKI-258) 51 FLT3,c-Kit,FGFR1
Linifanib (ABT-869) 33 CSF-1R,FLT3,Kit
Vatalanib (PTK787) 2HCl 52 PDGFRβ,c-Kit,c-Fms
RAF265 (CHIR-265) 23 B-Raf
Motesanib Diphosphate (AMG-706) 12 Kit,RET,PDGFR
Brivanib (BMS-540215) 10 FGFR1
MGCD-265 analog 12 Met,RON,Tie-2
AEE788 (NVP-AEE788) 13 EGFR,HER2/ErbB2,c-Abl
ENMD-2076 9 FLT3,RET,Aurora A
OSI-930 7 CSF-1R,LCK,C-Raf
CYC116 10 Aurora A,Aurora B,FLT3
Ki8751 20 c-Kit,PDGFRα
Telatinib 5 c-Kit,PDGFRα
KRN 633 6 PDGFRα,c-Kit,BTK
SAR131675 31
Apatinib (YN968D1) mesylate 24 RET
BMS-794833 1 Met
Brivanib Alaninate (BMS-582664) 2 FGFR1
Golvatinib (E7050) 8 c-Met
Semaxanib (SU5416) 20
ZM 323881 HCl 18
ZM 306416 13 Src,Abl
Sitravatinib (MGCD516) 4 DDR2,EPHA3,Axl
BFH772 0
BAW2881 (NVP-BAW2881) 2 C-Raf-1,B-RAFV599E,c-Abl
SU5402 19 FGFR1,PDGFRβ
Dovitinib (TKI258) Lactate monohydrate 31 FLT3,c-Kit,FGFR1
LY2874455 14 FGFR2,FGFR1,FGFR4
SKLB1002 4
AZD2932 3 PDGFRβ,Flt3,c-Kit
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Ranibizumab (Anti-VEGFA) is a recombinant humanized IgG1 monoclonal antibody fragment that inhibits (VEGF-A) and degrades angiogenesis throughout the body and in the eye also interrupts the interaction of VEGF with its receptors, and thus prevents the subsequent growth of new blood vessels.

Product Details

CAS No. 347396-82-1
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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