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Angiotensin Receptor
Angiotensin Receptor Products
- All (21)
- Angiotensin Receptor Inhibitor (1)
- Angiotensin Receptor Activator (1)
- Angiotensin Receptor Antagonists (19)
- New Angiotensin Receptor Products
| Catalog No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S5067 | Losartan | Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement. | ||
| S1578 | Candesartan | Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
|
| S7098 | PD123319 | PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
|
|
| S1359 | Losartan Potassium | Losartan Potassium is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
|
|
| S7678 | Sacubitril/valsartan (LCZ696) | Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3. |
|
|
| S1738 | Telmisartan | Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. |
|
|
| S1507 | Irbesartan | Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
|
|
| S1894 | Valsartan | Valsartan is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure. |
|
|
| S2037 | Candesartan Cilexetil | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension. |
|
|
| S8695 | ML221 | ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively. | ||
| S4102 | Eprosartan Mesylate | Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. |
|
|
| S3046 | Azilsartan | Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM. |
|
|
| S1604 | Olmesartan Medoxomil | Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure. |
|
|
| S6665 | Sparsentan (PS-433540, RE-021) | Sparsentan (PS-433540, RE-021, DARA) is a dual endothelin type A receptor(ETA) and angiotensin II type 1 receptor antagonist. | ||
| E0039 | A-779 | A-779 is a potent and selective antagonist for Angiotensin-(1–7) (Ang-(1-7)) with an IC50 of 0.3 nM in a radioligand binding assay. A-779 shows no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. |
||
| S3057 | Azilsartan Medoxomil | Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2. |
|
|
| S5581 | Olmesartan | Olmesartan (RNH-6270) is an an angiotensin 2 receptor antagonist with antihypertensive activity. | ||
| S4975 | Fimasartan | Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure. | ||
| E1015New | Angiotensin II human | |||
| S0326 | Olodanrigan (EMA401) | Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. | ||
| S5980 | Losartan Carboxylic Acid (EXP-3174) | Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM. | ||
| S7678 | Sacubitril/valsartan (LCZ696) | Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3. |
|
|
| E1015New | Angiotensin II human | |||
| S5067 | Losartan | Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement. | ||
| S1578 | Candesartan | Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
|
| S7098 | PD123319 | PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
|
|
| S1359 | Losartan Potassium | Losartan Potassium is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
|
|
| S1738 | Telmisartan | Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. |
|
|
| S1507 | Irbesartan | Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
|
|
| S1894 | Valsartan | Valsartan is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure. |
|
|
| S2037 | Candesartan Cilexetil | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension. |
|
|
| S8695 | ML221 | ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively. | ||
| S4102 | Eprosartan Mesylate | Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. |
|
|
| S3046 | Azilsartan | Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM. |
|
|
| S1604 | Olmesartan Medoxomil | Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure. |
|
|
| S6665 | Sparsentan (PS-433540, RE-021) | Sparsentan (PS-433540, RE-021, DARA) is a dual endothelin type A receptor(ETA) and angiotensin II type 1 receptor antagonist. | ||
| E0039 | A-779 | A-779 is a potent and selective antagonist for Angiotensin-(1–7) (Ang-(1-7)) with an IC50 of 0.3 nM in a radioligand binding assay. A-779 shows no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. |
||
| S3057 | Azilsartan Medoxomil | Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2. |
|
|
| S5581 | Olmesartan | Olmesartan (RNH-6270) is an an angiotensin 2 receptor antagonist with antihypertensive activity. | ||
| S4975 | Fimasartan | Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure. | ||
| S0326 | Olodanrigan (EMA401) | Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. | ||
| S5980 | Losartan Carboxylic Acid (EXP-3174) | Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM. | ||
| E1015New | Angiotensin II human |
Choose Selective Angiotensin Receptor Inhibitors
Tags: Angiotensin Receptor inhibitor|Angiotensin Receptor agonist|Angiotensin Receptor activator|Angiotensin Receptor inducer|Angiotensin Receptor antagonist|Angiotensin Receptor signaling pathway|Angiotensin Receptor assay kit
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